​

​First Key

Facilitate Awareness

• Educate others about DMD through gatherings, traditional media, and social media

​Second Key

Improve Quality Of Care & Life For Those Living With DMD

• Support Emergency Covid 19 Relief for DMD Families
• Award thirty five-hundred dollar grants during the winter of 2021 as part of The JB's Keys to DMD New England Winter Relief Fund 
• Sponsor Parent Project Muscular Dystrophy's Conference: Duchenne in the Brain, Depression and Anxiety in Duchenne 
• Execute the JB's Keys to DMD Educational Scholarship
• Support The Duchenne Program at UMassMemorial Center with Charley's Fund
• JB's Keys Adaptive Sports Scholarship for Skiing and Sailing ​
• Family Assistance Program with Team Joseph

​Third Key

Fund Advancing Research For A Cure

CRISPR/CAS 9 
Project led by Dr. Eric Olson from University of Texas, Southwest. Utilizing an advanced gene editing technology this strives to stop the progression of DMD in animal and human cells.

Cardiac Project
Expansion of the Department of Defense Grant to Dr. Elizabeth McNally at Northwestern University. This grant supports a focus on innovative ideas that will lead to substantial improvement in the care and treatment of Duchenne cardiomyopathy. 

Follistatin gene therapy trial 
Phase I/IIa trial in boys with Duchenne following a trial in Becker muscular dystrophy patients. Follistatin inhibits the myostatin pathway, which has shown to cause significant enlargement of muscle mass and increased muscle strength.

Carmeseal-MD
A treatment for heart failures and a potential skeletal muscle enhancer.  

GALGT2
A surrogate gene therapy for DMD that uses a viral gene transfer vector to deliver the GALGT2 gene. In animal models, delivery of GALGT2 results in a change to glycosylation across the entire muscle membrane, with upregulation of utrophin and other proteins that stabilize the muscle membrane, resulting in correction of muscle pathology and force deficits. This is a particularly promising approach because it is a potential therapy for any boy with DMD, regardless of mutation.

Relaxin
Relaxin is a natural hormone, which has a number of biological effects that may be of benefit in Duchenne Muscular Dystrophy (DMD), including its ability to regenerate muscle, reduce scarring and improve cardiac function. ​

Quercetin (nutraceutical)
Determining the mechanisms whereby a quercetin enriched diet interrupts disease processes in DMD.